Combination Smart

Smart combination therapy for liver cancer tackles drug resistance

Credit: CC0 Public Domain Liver cancer is one of the most common cancer types worldwide and is especially common in China. A collaborative effort between researchers at the Netherlands Cancer Institute and Shanghai using CRISPR/Cas has led to the discovery that insensitivity to a liver cancer drug can be prevented if it is given in…

Combination Horses

Beer and horses?

Combination takes to the electronic space with branded NFTs By Cointelegraph

Beer and horses? Combination takes to the digital space with branded NFTs The United Kingdom arm of pilsner beer brand Stella Artois is partnering with a digital horse racing game to release a series of nonfungible tokens (NFTs).In a Tuesday announcement from Stella Artois’ U.K. brewery, the beer brand said users of the digital racing…

Combination shows

Combination Shows Promise at Post-Osimertinib Lung Cancer

More than a third of lung cancers that progressed on osimertinib (Tagrisso) responded to combined targeting of EGFR, a subgroup analysis of an early clinical trial showed. Results in 45 patients showed one complete response and 12 partial responses to the bispecific antibody amivantamab (Rybrevant) targeting EGFR and MET and the third-generation EGFR tyrosine kinase…

Combination Therapy

Combination Therapy Achieves High Response in Ph+ ALL

A combination of ponatinib (Iclusig) and blinatumomab (Blincyto) achieved high rates of complete molecular remission and durable responses in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), according to results of a phase II study. Newly diagnosed Ph+ ALL patients treated with the combination had complete response and complete molecular response rates of 100%…

Combination Immunotherapy

New combination immunotherapy plus ART expand innate cells Crucial to controlling HIV

ATLANTA – Yerkes National Primate Research Center researchers in collaboration with Institut Pasteur have determined a combination immunotherapy of Interleukin-21 (IL-21) and interferon alpha (IFN?) when added to antiviral therapy (ART) is effective in generating highly functional natural killer (NK) cells that can help control and reduce simian immunodeficiency virus (SIV) in animal models. This…